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18 juillet 2013 4 18 /07 /juillet /2013 07:26
The EMBO Journal (2013) 32, 1972 - 1974 doi:10.1038/emboj.2013.140 Published online: 7 June 2013 There is an Article (July 2013) associated with this Have you seen?. Urs Jenal1 Biozentrum, University of Basel, Basel, Switzerland Correspondence to: Urs Jenal, urs.jenal@unibas.ch It has long been speculated that the bacterial second messenger c-di-GMP, a key molecular switch of bacterial community behaviour and persistence, can trigger specific cellular processes both on a global level as well as through some local action that prevents crosstalk originating from rapid diffusion of the signalling molecule. In this issue, Lindenberg et al (2013) report on a mechanism that not only helps to explain how spatial sequestration of c-di-GMP signalling components could be organized within bacterial cells, but also demonstrates how global and local command levels are interconnected.

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