Overblog Suivre ce blog
Editer l'article Administration Créer mon blog
23 avril 2011 6 23 /04 /avril /2011 09:57
Med Hypotheses. 1998 Jun;50(6):481-2.

Psoralens in association with seasonal affective disorder.

Source

Department of Psychiatry, University of Helsinki, Finland.

The pathogenesis of seasonal affective disorder (SAD) has been attributed to abnormal melatonin metabolism.

Perorally administered psoralens increase the daytime levels of melatonin via the competitive inhibition of hepatic melatonin metabolism.

Some findings among SAD patients are parallel to those observed after the administration of a psoralen in healthy subjects.

It is hypothesized that there may be a circulating psoralen-like substance which affects SAD patients under a low level of illumination.

Exposure to bright light during the daylight period would normalize the abnormal effect independently of the season.

Partager cet article

Repost 0
Published by Chronimed - dans Nutrition
commenter cet article

commentaires