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10 avril 2011 7 10 /04 /avril /2011 07:46

Brian J. Ward


MSc; MDCM; DTM&H; Associate Professor

Research interests

My laboratory is currently active in three areas:

1) the immunologic evaluation of vaccines and vaccine safety,

2) the evaluation of micronutrient-microbial interactions, and

3) the development of novel therapeutic strategies for microbial pathogens.


The laboratory is biased towards the discovery and implementation of practical solutions to microbial challenges but most projects are designed to examine problems mechanistically as well.

Although a good deal of the work performed in the laboratory takes place in Montreal, many of the projects have significant or even predominant components overseas.

There is a long-standing commitment in the laboratory to collaborative work with developing world researchers in Peru and Zimbabwe.

During the last 10 years, projects have been carried out in these countries as well as the USA, Haiti, Sudan and Brazil.


1) Vaccine evaluation and development

Active projects at the current time include the development of a Canadian network of vaccine evaluation centres, immunologic studies of measles, varicella and pertussis vaccines, development of proteosome-based vaccines for protozoan pathogens (leishmania, toxoplasmosis) and studies to develop an anti-myeloma vaccine.

This work is currently supported by the MRC, the Zellers Foundation, and various industry partners.

2) Micronutrients and microbial pathogens

Active projects include a large prospective trial of vitamin A to interrupt maternal-to-child HIV transmission in Zimbabwe, the role of HLA-G and HLA-E molecules in maternal-to-child transmission of HIV, basic studies of retinoids-paramyxovirus interactions (e.g., replication, nuclear retinoid signalling, apoptosis).

This work is currently funded by CIDA, USAID, the Rockefeller Foundation, the Elizabeth Glaser Foundation, and industry.

3) Novel therapeutic strategies for microbial pathogens

We are also exploring novel therapeutic agents for protozoal, fungal and bacterial infections.

Examples include a field evaluation of imiquomod for cutaneous leishmaniasis, development of class C-specific and pan-beta-lactamase inhibitors and a field-laboratory evaluation of the potential for lectins as anti-parasitic agents.

This work is currently supported by the WHO, the Thrasher Foundation, and industrial partners.


Rhodes Scholarship
Quebec: Corpus Christi

Departmental affiliation

Medicine; Microbiology and Immunology; Parasitology

Accepting students from

Experimental Medicine; Parasitology; Microbiology and Immunology

Mis en ligne le 29 novembre 2009

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alarm piscine 07/11/2011 23:17

Robot de cuisine piscine mécanique des fluides : Les robot de cuisine nettoyeuse hydrauliques allant vis-à-vis l'ingénierie de la respiration amortissent la grande pompe de filtration de la
comme agent de nerf. Elles se connectent touchant le skimmer voir divisé par la prise balai-brosse de la piscine mais aussi demeurent en état de marche sans décoration imprévu.