Overblog Suivre ce blog
Editer l'article Administration Créer mon blog
23 avril 2011 6 23 /04 /avril /2011 09:49
Arch Pharm Res. 1999 Jun;22(3):324-6.

Inhibitory activity of monoamine oxidase by coumarins from Peucedanum japonicum.

Source

College of Pharmacy, Chungnam National University, Taejon, Korea.

 

Four coumarins were isolated from chloroform extract of the root of Peucedanum japonicum and identified as praeruptorin A(1), xanthotoxin (2), psoralen (3) and bergapten (4) on the basis of spectroscopic methods.

 

The inhibitory activities of these coumarins on monoamine oxidase prepared by mouse brain were tested. The IC50 values of them were shown to be 27.4 microM (1), 40.7 microM (2), 35.8 microM (3), and 13.8 microM (4), in vitro.



PMID:
 
10403141
 
[PubMed - indexed for MEDLINE]

Partager cet article

Repost 0
Published by Chronimed - dans Nutrition
commenter cet article

commentaires