Overblog Suivre ce blog
Editer l'article Administration Créer mon blog
21 avril 2012 6 21 /04 /avril /2012 18:35
In Vivo. 2010 Sep-Oct;24(5):799-802.
Reduced side-effects of adjuvant hormone therapy in breast cancer patients by complementary medicine.
Uhlenbruck G, VAN Leendert R, Schneider B, Beuth J.
Source
Institute of Immunobiology, University of Cologne, Germany.
Abstract
A clinical investigation (representing evidence-based medicine level III) was performed to evaluate the benefit of complementary medicine in breast cancer patients undergoing adjuvant hormone therapy (HT).
PATIENTS AND METHODS:
The patients (n=129) were treated according to international guidelines. All patients suffered from arthralgia and mucosal dryness induced by the adjuvant HT. To reduce these side-effects, the patients were complementarily treated with a combination of sodium selenite, proteolytic plant enzymes (bromelaine and papain) and Lens culinaris lectin. On the basis of case report formulas (CRFs), self assessment of defined side-effects of HT (arthralgia and mucosal dryness) were documented before as well as 4 and 8 weeks after complementary treatment. Validation was carried out by scoring from 1 (no side-effects/optimal tolerability) to 6 (extreme side-effects/extremely bad tolerability).
RESULTS:
The severity of side-effects of HT was reduced by complementary treatment with sodium selenite, plant enzymes (bromelaine and papain) and Lens culinaris lectin. The mean score of symptoms declined from 4.2 (before treatment) to 3.2 (after 4 weeks of treatment) to 2.7 (after 8 weeks of treatment) for arthralgia and from 3.2 (before treatment) to 2.9 (after 4 weeks of treatment) to 2.6 (after 8 weeks of treatment) for mucosal dryness, the primary aims of this investigation. The reduction of side-effects of HT was statistically significant (p

Partager cet article

Repost 0
Published by Chronimed - dans Nutrition
commenter cet article

commentaires