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21 juillet 2012 6 21 /07 /juillet /2012 08:21
Research Highlight Nature Reviews Drug Discovery 11, 516-517 (July 2012) Darren J. Burgess Anticancer drugs: Antipsychotic to anticancer agent? Darren J. Burgess Abstract The selective targeting of cancer stem cells (CSCs) to induce either differentiation or apoptosis remains an attractive therapeutic approach, even though there is uncertainty about precisely what defines a CSC. A new study has devised a high-throughput platform to screen for compounds that selectively differentiate CSC-like cells and has identified dopamine receptor antagonists as promising candidates.

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